The patch is applied to the skin, and fentanyl, being lipid-soluble, is able to permeate the skin and is gradually released in the general circulation. A polymer membrane between the fentanyl reservoir and the adhesive layer controls the rate of fentanyl release from the reservoir. The layer that adheres to the skin has a silicone adhesive, whereas the outermost backing layer is made of polyester. The transdermal fentanyl patch is a transparent, rectangular unit that has a fentanyl reservoir sandwiched between an adhesive layer and a backing layer. Transdermal fentanyl patches are indicated for the management of chronic pain only in individuals who have developed tolerance to other opioids and require continuous opioid therapy. What is a Fentanyl Patch?Ī fentanyl patch is a delivery system used to administer fentanyl in a rate-controlled manner for 72 hours. Being aware of the risks of using a fentanyl patch can help to prevent an overdose or addiction. Fentanyl is a very potent opioid and can cause a fatal overdose. However, fentanyl has high abuse potential, and transdermal patches may be misused for their euphoric effects. Transdermal fentanyl patches are applied to the skin and are designed for gradual delivery of fentanyl in fixed doses. Fentanyl is indicated for use only in patients who are not responsive to the analgesic effects of other opioids, perhaps due to having developed a tolerance to other opioids.įentanyl delivered by oral or intravenous routes is used for the treatment of acute pain, whereas transdermal fentanyl patches are indicated for chronic pain that requires around-the-clock opioid treatment.
Fentanyl is 50 to 100 times more potent than morphine and is used only when other forms of treatment do not provide adequate analgesia. Fentanyl is a synthetic opioid that is used for the treatment of acute or chronic, severe pain.
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